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To be eligible, you'll generally need a BMI of 35 or higher, or a lower BMI plus a qualifying condition like heart failure, chronic kidney disease or prediabetes the full eligibility criteria are slightly more restrictive than those for a GLP-1 prescription itself

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Cardiovascular exercise: Moderate cardio (walking, cycling, swimming) 3 to 5 times per week supports heart health and additional calorie burn without excessive stress on recovery

The percent mediated was calculated as the (total effect direct effect) / total effect 100%, and the standard error (and, hence, the 95% CI) of the percent mediated was estimated using the delta method