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CagriSema and Retatrutide are investigational compounds and are not FDA-approved for human treatment as described here

Even with the availability of effective drugs to treat diabetes mellitus, DN remains the leading cause of end-stage renal disease worldwide (Mestry et al., 2017)

[11] [12] FDA-approved GLP-1 agonists include semaglutide (Ozempic, Wegovy, Rybelsus), dulaglutide (Trulicity), liraglutide (Victoza, Saxenda), and exenatide (Byetta, Bydureon), among others