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2f), and improved insulin sensitivity relative to vehicle-treated controls, as indicated by direct assessment of insulin tolerance (Fig
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The bedtime timing matters because the goal is to amplify a pulse that would otherwise occur naturally during deep sleep, not to introduce a daytime pulse that conflicts with normal pituitary rhythms
Ultra-fine needles and topical anaesthesia ensure comfort throughout treatment
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R., de Oliveira, E
2014;4:e004376 Funding This study was funded by Enterprising Birmingham, University of Birmingham, UK, from 1st August 2016
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