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Evidence from SURPASS CVOT is awaited to assess whether these benefits on surrogate markers will translate into actual MACE prevention

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injection of exenatide dampened cocaine-driven septal dopamine elevation, mediated by postsynaptic GLP-1R signaling that retrogradely regulates presynaptic dopamine transporter function [106]

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As exendin 939 had the lowest IC 50 value for inhibiting CAP-activated TRPV1 currents, its molecular mechanism was further analyzed

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