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Women of childbearing potential should be counseled that Wegovy should be discontinued at least 2 months before a planned pregnancy

Removing the injection requirement is a bigger deal than it sounds

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See FDA prescribing information for semaglutide (Wegovy) and tirzepatide (Zepbound) via FDA Drugs@FDA

Although there was no incidence of a DKA event, two participants experienced recurrent euglycemic ketosis without acidosis [11]

This can result from reduced caloric intake, blood sugar adjustments, or the body adapting to GLP-1 receptor activation