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Overview of the available GLP-1RAs listed according to their reported half-lives ( t 1/2 ) and the current clinical evidence of their effect in treatment of BAD Here, we review the scarce literature on the use of different GLP-1RAs in BAD treatment and discuss the potential of different GLP-1RAs in the context of their pharmacokinetic profiles, which we speculate may be important determinants of their mode of actions and, thus, pharmacodynamics in BAD

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Janumet (sitagliptin/metformin) for type 2 diabetes Janumet is an oral prescription medication designed to treat type 2 diabetes

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Competitive Landscape The Asia-Pacific glucagon-like peptide-1 (GLP-1) agonists market is consolidated with key manufacturers namely Eli Lilly, Sanofi, Novo Nordisk, and AstraZeneca etc

However, as the streptozotocin model primarily reflects severe insulin deficiency, the findings may not fully capture the complexity of type 2 diabetesrelated cognitive dysfunction