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Eligible patients will be offered education and support from NHS staff to enable them to safely administer their own B12 injections, or have them administered by a family member or carer

PQQ is generally well-tolerated when taken at standard supplemental doses

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The FDA-approved compound in the melanogenesis pathway is afamelanotide, the linear 13-mer parent, approved only for erythropoietic protoporphyria

Always consult your prescribing clinician before combining supplements with your medication, and monitor energy and gastrointestinal tolerability over the first 2 to 3 weeks