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In abdominal aorta anastomosis models, the peptide prevents and reverses thrombus formation, suggesting antithrombotic effects mediated through endothelial protection and normalized coagulation cascade activity

Over weeks of consistent dosing, this translates into clinically measurable improvements in nerve fiber density and sensory function

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Amylin receptors are heterodimers of the class B calcitonin G protein-coupled receptor (CTR) and receptor-activity modifying proteins (RAMPs)