10.1186/s12933-018-0728-6 6
This creates a cascade of problems
The phase 2a liver-specific trial showed: 1 mg dose: 42.9% reduction in liver fat 4 mg dose: 57.0% reduction in liver fat 8 mg dose: 81.4% reduction in liver fat 12 mg dose: 82.4% reduction in liver fat An 82% reduction in liver fat is extraordinary
And while some research suggests growth hormone may have certain health benefits, there's very little evidence showing that CJC-1295 delivers the outcomes being promised, particularly for women in perimenopause and menopause
Acid reflux emerged as a reported concern in GLP-1 clinical trials, with roughly 2030% of semaglutide users describing heartburn or reflux symptoms in early weeks of treatment
Primary endpoints included cataracts, oculomotor binocular dysfunction, visual impairment and blindness, visual disturbances, dry eye disease, and ametropic accommodative dysfunction, all identified through ICD-10-CM coding (Supplementary Data 3)