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Genotoxicity testing, which evaluates whether a compound can damage DNA, found no evidence that 5-amino-1mq causes genetic damage
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A potential mode of action for the combination of DFX with doxorubicin might be an increase of the intracellular calcium resulting in an improved sensitivity to chemotherapy in leukemia cell lines (138)
Histological analysis showed that FOXO4-DRI treatment improved the testicular microenvironment, leading to thicker seminiferous epithelia, increased spermatogenic cells, and more mature spermatozoa in the central lumen
This is the deepest limitation, and no arithmetic solves it
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