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For those with a B12 deficiency and an MTHFR mutation, one major advantage of B12 injections is that they are readily absorbed in the body and do not have to be taken as often as oral tablets

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doi:10.1016/j.bcp.2017.11.007 (PMID 29155147) Neelakantan H, Brightwell CR, Graber TG, et al

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"The Brain-Gut Connection." Johns Hopkins Medicine