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However, specific injuries such as traumatic brain injury, stroke, brain tumor, or aging are believed to compromise the efficiency of BBB protection, thereby allowing MSCs access to cross the BBB and deliver their protective effects

No changes in cancer markers, hormones, liver, or kidney function reported (only monitored in the short term days)

Galloway, D.C., Blacke, D.G., Shepherd, A.G

It also appears to exert a protective effect on the gut-brain axis, reducing symptoms of anxiety and stress-induced damage through modulation of serotonin and dopamine systems