In off-label clinical practice, doses range from 1 mg to 2 mg daily depending on the patients baseline IGF-1 levels, tolerance, and treatment goals
Taking more than recommended does not improve results and can increase side effects
Peer review Peer review information Nature Communications thanks Massimiliano Cerletti, and the other, anonymous, reviewer(s) for their contribution to the peer review of this work
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We then sought to explore the involvement of A2AR-mediated downstream signal pathways such as protein kinase A (PKA) in modulation of GSH metabolism