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Week 24: First Major Published Endpoint The Phase 2 obesity trial published in the New England Journal of Medicine and indexed on PubMed enrolled 338 adults and used week 24 as the primary body-weight endpoint
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Serotonin is mainly found in the GIT (Gastrointestinal tract), blood platelets, and the central nervous system of animals and humans
Rapid weight reductioncommon in the first months of treatment with these medicationsmay not allow sufficient time for physiological adaptation
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