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In any case parameters of glucose metabolism should be closely monitored at presentation and throughout active disease but also after cure of the underlying pituitary disease

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Preclinical studies in animal models have demonstrated that survodutide effectively activates both GLP-1R and GCGR, resulting in reduced body weight, slower gastric emptying, decreased energy intake, increased energy expenditure, and improved glucose tolerance [86]

Eur J Pharmacol 632(13):6572