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While standard L-carnitine is highly effective at facilitating physical energy production in muscle tissues, its ability to reach the central nervous system is notoriously limited
Methylglyoxal evokes pain by stimulating TRPA1
doi:10.1016/S0140-6736(25)01073-6
The specific dose can influence the peak concentration and the time it takes to reach a steady state, but the underlying half-life of the molecule itself generally remains constant across these therapeutic doses
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