This fact may help scientists understand how to decrease insulin doses in individuals who have decreased insulin sensitivity and may even offer insight into preventing type 2 diabetes in the first place
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However, some contraindications to GH therapy are present in subjects with PWS, such as severe obesity or severe respiratory impairment, acute critical illness, uncontrolled diabetes, active cancer, and active psychosis (118)
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61.7 12.4 years, p = 0.011)
Regarding plasma B12 - this is not the case, serum B12 often remains highly elevated (well over the normal range) even while symptoms return - this is why testing B12 once treatment begins is not recommended