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Because GHK binds Cu(II) tightly, it offers a controlled system for studying how copper may relate to collagen pathways, antioxidant enzyme activity, and gene-expression regulation

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To bridge this gap, the field must pivot from proof-of-concept studies to rigorous translational validation

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The authors extend their appreciation to the Deanship of Research and Graduate Studies at King Khalid University for funding this work through Small Research Project under grant number (RGP1/132/46)