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Despite advancements in understanding MAFLD pathogenesis, therapeutic targets, and drug development, no FDA-approved treatment for MAFLD currently exists [7]

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Identification and characterization of a novel human sphingosine-1-phosphate phosphohydrolase, hSPP2

In the highest-performing semaglutide trial, one in three participants achieved 20% or greater weight loss, a threshold rarely seen with pharmaceutical interventions