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Nrf2 knockdown prevents NFT-dependent increase in cellular glutathione levels To examine the correlation between Nrf2 activation and the increase in glutathione levels after NFT treatment, Nrf2 protein levels were experimentally lowered by siRNA-mediated knockdown, which was confirmed by Western blotting (Fig

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As increased fall risk may be a contributor to the fracture risk in diabetes ( In order to rule out differential mortality as a source of bias in our study, we estimated HRs of death in the two groups and found a negligible difference, although this became significant in the fully adjusted model

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