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This approach honors the reality that PCOS is metabolically heterogeneous and that precision dosing, informed by genetics, yields better outcomes and tolerability than standard escalation protocols

Recent studies have leveraged the abnormal vascular structure of tumors, and the size advantage of nanoparticles (typically less than 200 nm), to achieve selective accumulation at prostate lesions via enhanced EPR

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At baseline, demographic and disease characteristics were balanced between treatment groups

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