Jenkinson HF, Lala HC, Shepherd MG

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That pattern is what clinicians read as a therapeutic response, not a drug detection
Therefore, after SARS-CoV-2 infection, the immune system is up-regulated, promoting many different molecules that can act in the CNS by different pathways
Starting doses are sub-therapeutic by design, existing to allow gastrointestinal adaptation, yet some patients get appetite reduction and modest weight loss even there
These symptoms can be mild to severe and may require adjustments in dosage or discontinuation of the medication