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Layering on requirements for optimal pharmacological profiles and drug-like properties to support oral dosing adds another level of complexity. But acording to Terry Kenakin, a former GSK drug developer now at the University of North Carolina-Chapel Hill in the US, we are in what I call a renaissance in terms of finding compounds that modify the function of these [GPCR receptors]

Los expertos creen que la ralentizacin del vaciamiento gstrico causada intencionadamente por los agonistas del receptor GLP-1 podra ser responsable de estos problemas

"The FDA has already issued warning letters about compounded GLP-1s," she said

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Redox-sensitive fluorescent nanoparticles for biovisualization of malignant tumors

PLoS ONE 9 , e94151 (2014)