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found that rats developed columnar cell atypia resembling low-grade pancreatic intraepithelial neoplasia which is considered a precursor to cancer after 12 weeks of exenatide treatment (Gier et al., 2012b)

Two recent reviews make this clear

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Affecting the first two receptors means retatrutide may help suppress appetite and slow digestion, which can help users feel full after eating even smaller meals

Ostergaard, L., Frandsen, C

The complex of myxomas, spotty pigmentation, and endocrine overactivity