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Cardiovascular health: Those with hypertension, high cholesterol, or other cardiovascular issues may face elevated risks
However, these timelines are subject to change and depend on trial results and regulatory review
Additional warnings in the FDA prescribing information include: severe gastrointestinal adverse reactions, acute kidney injury, acute gallbladder disease, acute pancreatitis, serious hypersensitivity reactions, hypoglycemia risk when used with insulin or insulin secretagogues, diabetic retinopathy complications and vision changes in patients with type 2 diabetes, depression or mood changes requiring clinical monitoring, and pulmonary aspiration risk during general anesthesia or deep sedation
Some people also explore combining GLP-1 medications with other peptides like AOD-9604 alongside tirzepatide for enhanced fat loss, though data on such combinations is limited
Niel, G., DAngelo, G
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