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This apparent paradox likely reflects differences in host genetic background, microbial source, and epithelial metabolic state, which together determine whether butyrate functions predominantly as a homeostatic metabolite or as a pro-tumorigenic signal [208, 209]
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Colorimetric analysis revealed a 1.8% increase in L* value (skin lightness) and an 8.7% increase in individual typology angle (ITA) compared with placebo
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Exp Gerontol 43:176183
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