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Clinical trials demonstrate average weight reductions of approximately 15% with semaglutide 2.4 mg (STEP 1 trial) and 20-22.5% with tirzepatide 10-15 mg (SURMOUNT-1 trial) over 68-72 weeks
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O ensaio incluiu pessoas sem diabetes, com IMC mdio de 40,4kg/m, e ambas as doses atingiram todos os desfechos primrios e secundrios: reduo de peso, diminuio da dor (at 75,8% de reduo no escore de dor WOMAC) e melhora da funo fsica
Recognising Symptoms of Gallstones During GLP-1 Treatment Many individuals with gallstones remain asymptomatic, with stones discovered incidentally during imaging for unrelated conditions
Jenkins DJ, Wolever TM, Collier GR, Ocana A, Rao AV, Buckley G, et al
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