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This study shows that as new medications are approved we need to be careful as long term side-effects may be seen that we were not aware of. Diabetes is very common in our practices and many of our patients are put on the GPL-1s, Geffen continued
20.4% CagriSema Trial REDEFINE 2 (NEJM 2025) Duration 68 weeks Population T2D + BMI 27 (n=1,206) Mean Weight Loss 13.7% CagriSema vs 3.4% placebo
Even in non-obese individuals, GLP-1 medications can reduce systemic inflammation and improve insulin sensitivity, making them helpful for inflammatory or metabolic syndromes
Store in its packaging, away from light, heat and moisture
Weight loss during this phase typically averages 1.5-2.5 lbs weekly, with the majority coming from fat stores
Do different pills require different dosing strategies
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