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2 Monotherapy is no longer available in the USA since Jan 2023, and lixisenatide-glargine (iGlarLixi) has been approved for type 2 diabetes
Hence, while components of the DNA repair machinery in immune cells from aged individuals decrease compared to young-adult individuals, pro-inflammatory proteins are increased
[7] [8] This triple-action mechanism distinguishes it from currently approved therapies and is thought to underpin its potentially greater efficacy in weight reduction
9 :511S-518S
doi:10.1016/j.bbagen.2012.10.012 Ballatori N, Krance SM, Notenboom S, Shi S, Tieu K, Hammond CL