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Rapid weight loss in general regardless of the method can increase the risk of losing muscle and reducing bone density if nutrition intake and resistance exercise are not prioritised
Viader A, Sasaki Y, Kim S, Strickland A, Workman CS, Yang K, et al
and Zearalenol metabolites caused cytotoxicity by inhibiting cell viability, protein and DNA syntheses and inducing oxidative damage and over-expression of stress proteins
That being said, nobody is going to do a huge randomized controlled trial on compounded medication
Most GLP-1 patches sold online are made with herbal ingredients, not semaglutide or liraglutide
If your primary goal is weight loss, you might also ask about Wegovy, which is semaglutide specifically FDA-approved for weight management
