Phentermine is FDA-approved for short-term weight loss in people with a BMI of 30 or higher, or 27 or higher if they have weight-related health conditions
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Experts estimate that Zepbound claims for severe gastrointestinal complications could reach between $400,000 and $700,000
patients should be screened for mood disorders, monitored for emerging depressive symptoms or suicidal thoughts, and the drug avoided in individuals with a history of suicide attempts or active suicidal ideation. Finally, delayed gastric emptying raises perianesthetic aspiration concerns
Nutrients (2020) 12(1):222
As the medications become increasingly popular (and are due to become cheaper in 2026, when generic versions will hit production), its important to consider the positives and negatives and to be realistic about the effects of these drugs on health and performance