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Patients with a history of cobalt allergy may be at increased risk, as all cobalamins (including hydroxocobalamin and cyanocobalamin) contain a cobalt atom in their molecular structure

B12 is typically absorbed through the stomach, so if you havestomach issues or have taken many common medications you may not be able to absorb it as effectively

Which claims rest on human trials, which rest on rat studies, and what is unsafe.