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It is likely safe to take year round

Several factors can affect results: Age and sex Pregnancy Fasting status Hydration Recent exercise Acute illness Supplements and other medications Anemia Kidney function Weight and body-composition changes Laboratory methodology An abnormal result does not always indicate disease, and a normal result does not always exclude a clinically important problem

Tulchinsky TH, Varavikova EA, Cohen MJ

GLP-1 Receptor Agonists and Cardiometabolic Effects

The symptoms of cobalamin deficiency are similar to the symptoms of the diseases that typically lead to cobalamin deficiency

It is also important for the normal functioning of the nervous system