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The study protocol was amended from version 1 to version 2 prior to enrollment of the first participant to add tirzepatide as an incretin mimetic therapy and to designate AEs of special interest (pancreatitis, liver injury, depression/suicidality and creatine kinase elevations)
2016;41(10)(Diabetes suppl):3-6
However, limited long-term human lactation studies exist for either compound, which explains why many manufacturers note breastfeeding as a consideration rather than an absolute contraindication
Phentermine reduces appetite by elevating the number of neurotransmitters in the brain
Arora, 2007
Monitoring these parameters can help in adjusting the treatment plan if necessary, ensuring each patients safety and well-being
