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Additionally, there were improvements in various cardiometabolic markers. The most common side effects were gastrointestinal, she reported, and occurred primarily during dose escalation
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Medication review is essentialdose reduction or temporary discontinuation may be necessary if side effects are severe, and concurrent medications (particularly insulin or sulfonylureas) may require adjustment
10.1126/science.1072994 Science 25 HlscherC
& Duca, F
Hyman M
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