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An extract of the fruit seed has been and is currently being studied for its benefits in supporting leptin sensitivity (one of the anorexigenic neuropeptides) , and weight loss management.* Irvingia gabonensis (African Mango) is high in soluble fiber which is suggested to support healthy lipid levels, in conjunction with a normal diet and moderate exercise in overweight individuals.* It has also shown the ability to help slow the rate of carbohydrate absorption as well as having a potential starch blocking effect.* Fat cells (adipocytes) secrete a hormone called leptin that tells our brain (in the hypothalamus) we have eaten enough
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A Note on Where the Science Stands It is important to be clear about the current state of this evidence
Effects described in reports and user accounts include nausea, vomiting, facial flushing, decreased appetite, priapism, an allergic reaction in some cases, and heightened sun sensitivity
GLP-1 exerts its biological effects by binding to a specific receptor (GLP-1R), which is expressed in different types of peripheral tissues and in the central nervous system [12]
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