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Butyrate is the key metabolite that unifies and supports the benefits of this synbiotic system.*1-3

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The upregulation of ovarian tumor deubiquitinase 5 deubiquitinates and stabilizes GPX4, reversing 4-HNE-induced ferroptosis, revealing the mechanistic role of 4-HNE in GPX4-dependent ferroptosis [32]

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