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In pregnant rabbits given 0.2, 2, 22, 156, or 260 mcg/kg/day exenatide during fetal organogenesis, irregular fetal skeletal ossifications were observed at 2 mcg/kg/day, a dose yielding systemic exposure up to 12-times the human exposure from the MRHD of BYETTA based on AUC comparison

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Vardi, Y

Soboll S, Gruendel S, Harris J, Kolb-Bachofen V, Ketterer B, Sies H (1995) The content of glutathione and glutathione s-transferases and the glutathione peroxidase activity in rat liver nuclei determined by a non-aqueous technique of cell fractionation

10.1016/j.peptides.2014.08.014 Peptides 40 LiX

Alzheimer disease and oxidative stress