Several large cardiovascular outcomes trials included kidney endpoints as secondary or exploratory outcomes and consistently pointed toward renal benefit
Jones, G
Mller-Schssele SJ, Wang R, Gtle DD, Romer J, Rodriguez-Franco M, Scholz M, Buchert F, Lth VM, Kopriva S, Drmann P, Schwarzlnder M, Reski R, Hippler M, Meyer AJ (2020) Chloroplasts require glutathione reductase to balance reactive oxygen species and maintain efficient photosynthesis
These side effects are dose-dependent and typically improve with time and proper dose titration
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Choosing between these drugs depends on medical history, how your body responds, and your individual preferences