India faces a massive and growing burden of metabolic disease: * 100+ million people living with diabetes * A rapidly rising obesity epidemic * Increasing cardiometabolic risk across age groups The arrival of more affordable GLP-1 therapies could reshape treatment pathways and dramatically expand access
At the 12 mg dose level, here is what clinical trials reported: Nausea: 43.2% of participants (versus 10.7% on placebo) Diarrhea: 33.1% of participants (versus 13.4% on placebo) Constipation: 25.0% of participants (versus 8.7% on placebo) Vomiting: 20.9% of participants These percentages tell an important story
In many cases, they take years to fully materialize
Integrated telehealth platforms are included
Innovative Solutions: Discover how sponsors can support sites through flexibility and innovative protocol design, and how sites can support sponsors through robust enrollment and retention programs Case Studies and Best Practices: Learn about recent real-world scenarios and best practices for successfully navigating the challenges of developing GLP-1s from bench to bedside, and what lessons can be applied to your own studies
doi: 10.1056/NEJMoa1509225 48 BolliGBMunteanuMDotsenkoSNiemoellerEBokaGWuYet al