Tirzepatide at all doses outperformed semaglutide in HbA1c reduction, weight loss, and lipid improvements
21 Similarly, a prospective case series of 14 patients with both HS and obesity treated with liraglutide 3 mg for 3 months demonstrated reductions in BMI, waist circumference, systemic inflammatory markers like CRP, homocysteine and plasma cortisol, and DLQI
Use evidence-based, third-party tested products and avoid blends that hide proprietary doses
Nutritional Guidance Proper protein intake and nutrient timing help support lean body mass
If you're on a high dose of semaglutide near the top-end of what the manufacturers recommend, or even more if you're going off-label with compounded semaglutide then you may experience more of a drop from missing a dose, especially if you don't notice right away
Muscle loss can lower calorie burn