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Some complications improve with appropriate treatment, but others, such as problems with the nervous system, can sometimes be permanent
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These mice spontaneously developed a lupus-like disease, while complete ablation of GPX4 in neutrophils caused severe neutropenia but no lupus-like disease, which again provides evidence for the importance of neutrophils in SLE pathogenesis (Fig 1)
They are often discussed in aging research because they are connected to cellular aging and long-term cell function
doi:10.3389/fendo.2013.00009
Glutathione transferases as efficient ketosteroid isomerases
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