In cultured hippocampal neurons, Dihexa treatment for 5 days induced a near 3-fold increase in the number of actin-enriched spines by 41 spines/50m for Dihexa vs
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Subcutaneous injections are perfect for certain doses of delicate drugs
But by walking through the mechanisms, early data, and practical considerations, we can at least distinguish biochemical plausibility from marketing hype