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Hepatic glutathione content decreased to 1.29 mol/g liver (25.5% compared to control) after DEM treatment, and there were no apparent hepatotoxic signs estimated by blood chemistry examinations
Dose interruptions or reductions may be required for side effects (e.g., high hemoglobin, hypertension, bone pain)
People who did not get the weight reduction they wanted with semaglutide or tirzepatide can get this too
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In steroidogenic tissues, such as the placenta, ovaries, testes, and adrenal cortex, it is used to hydroxylate intermediates in the conversion of cholesterol to steroid hormones, a process that makes these hydrophobic compounds more water soluble
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