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Pharmaceutical companies must typically invest many years and hundreds of millions of dollars to win approval for a drug

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Improving Care and Promoting Health in Populations: Standards of Care In Diabetes2024

This process is particularly important for energy generation from fat stores during sustained exercise or calorie restriction

On top of this, chronic stress raises cortisol, which may promote fat storage, particularly around the midsection, and stall progress even when diet and exercise are dialed in