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In short, AT under obese conditions due to the presence of many pro-inflammatory factors and iron accumulation, which may trigger the occurrence of ferroptosis and inflammation in M2, eventually leads to high rates of adipocytes proliferation and further development of obesity

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One such peptide in the tissues is Epithalamin, naturally produced in the pineal gland

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One study with volunteers found even people without sensitive skin experienced a significant reduction in stratum corneum integrity and induced mild erythema