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PMID: 10499368
Theyre more likely to cause discomfort, inflammation, or even pain during or after the injection, which can make regular dosing unpleasant and less sustainable
All doses below come from published clinical trials, manufacturer guidelines, and established practitioner protocols as of February 2026
Galon J, Mlecnik B, Bindea G, Angell HK, Berger A, Lagorce C, Lugli A, Zlobec I, Hartmann A, Bifulco C, Nagtegaal ID, Palmqvist R, Masucci GV, Botti G, Tatangelo F, Delrio P, Maio M, Laghi L, Grizzi F, Asslaber M, D'Arrigo C, Vidal-Vanaclocha F, Zavadova E, Chouchane L, Ohashi PS, Hafezi-Bakhtiari S, Wouters BG, Roehrl M, Nguyen L, Kawakami Y, Hazama S, Okuno K, Ogino S, Gibbs P, Waring P, Sato N, Torigoe T, Itoh K, Patel PS, Shukla SN, Wang Y, Kopetz S , Sinicrope FA, Scripcariu V, Ascierto PA, Marincola FM, Fox BA, Pags F
Yes, and it is increasingly common in longevity-focused clinics in South Florida and nationally