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PubMed Campbell, J.E., Ussher, J.R., Mulvihill, E.E., Kolic, J., Baggio, L.L., Cao, X., Liu, Y., Lamont, B.J., Morii, T., Streutker, C.J., Tamarina, N., Philipson, L.H., Macdonald, P.E., & Drucker, D.J
View Study [5]"Recombinant expression of IGF-1 and LR3 IGF-1 fused with xylanase in Pichia pastoris" Lu Z, Liu N, et al., 2023 Finding: Purified LR3 IGF-1 displayed excellent bioactivity for cell proliferation comparable to standard IGF-1, confirming that the molecular modifications preserve its biological function while extending its active lifespan
Kumar V, Maitra SS, Singh R, Burnwal DK (2020) Acclimatization of a newly isolated bacteria in monomer terephthalic acid (TPA) may enable it to attack the polymer polyethylene tere-phthalate (PET)
For context, human safety testing found no meaningful irritation from creams containing centella extract at everyday use levels (the tested amounts were well under 1%)