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doi: 10.1002/ar.21192 19 IzbekiFWittmannTJancsoGCsatiSLonovicsJ
Through the analysis of data from 19 randomized controlled trials, the researchers believe their work points to possible precision medicine applications of GLP-1s beyond just weight loss
The only FDA-approved oral GLP-1 is semaglutide (Rybelsus) for diabetes
Results aren't immediate, as it can take several weeks for the medication to have its full effect
This assumption can be misleading and dangerous
This sample size provides at least 80% power for the comparison of tirzepatide versus placebo for the change in energy intake during ad libitum test meals (primary outcome) based on a two-sample t -test at an alpha level of 0.05, given an expected treatment difference of 212 kcal and an assumed common standard deviation of 289 kcal for the change in energy intake from baseline
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