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SOD does not generally react with free radicals, only the superoxide anion

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For participants receiving 40 mg daily of oral semaglutide, three different dose-titration protocols were used where patients were titrated up to the full 40 mg dose in 6 weeks (fast dose escalation), 12 weeks (standard dose escalation), or 24 weeks (slow dose escalation)

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In addition, semaglutide can cause drowsiness and headaches 2